ADC quench reagents
4 listings from 4 suppliers · 2 Japanese makers
Japanese name: ADCクエンチ試薬（NAC・NEM）
ADC quench reagents cap the excess drug and maleimide left after conjugation and stop the reaction, in the termination step of ADC manufacturing. N-acetylcysteine (NAC) and N-ethylmaleimide (NEM) are typical. Because the point at which residual reactivity is suppressed affects the reproducibility of the drug-to-antibody ratio (DAR), buyers choose by compatibility with the reaction system. Here you will find NAC, NEM and related quench reagents by maker.
| Product | Maker | Where to buy in Japan |
|---|---|---|
| N-acetylcysteine (NAC), NEM | Merck | Merck Ltd., Japan (Japanese subsidiary, Life Science) |
| NAC and NEM quenching reagents | FUJIFILM WakoJP maker | From the maker |
| N-acetylcysteine, N-ethylmaleimide | TCIJP maker | From the maker |
| Quenching reagents (NAC / cysteine derivatives) | MedChemExpress | Not yet confirmed |
“Where to buy in Japan” shows only sales relationships we have confirmed on the company’s or the distributor’s own website. “Not yet confirmed” means we have not checked yet, not that the product is unavailable in Japan. Product names link to the maker’s own page.