Calibration

Comparing the readings of an instrument, or the value assigned to a standard, with a reference of higher order, and adjusting or recording the difference, so that measurements trace back to recognized standards. In GMP, critical instruments such as balances, temperature probes, pressure gauges and pH meters are calibrated on a schedule. An out-of-tolerance finding triggers an assessment of every product tested or made since the last good calibration. Japanese documents use both the native word and the loanword in the headword.