IVT enzymes reagents
6 listings from 6 suppliers
Japanese name: IVT用酵素・試薬（T7・NTP・DNase）
IVT enzymes and reagents are the enzymes and substrates used to synthesize mRNA from a DNA template by in vitro transcription: T7 RNA polymerase, NTPs, modified NTPs and DNase for removing the template. They supply the nucleic acid synthesis step of mRNA manufacturing. Suppliers differ in research and GMP grades and in the regulatory documentation they support. Below are IVT enzymes and nucleotides by maker.
| Product | Maker | Where to buy in Japan |
|---|---|---|
| TheraPure / GMP T7 RNA Polymerase, NTP | Thermo Fisher Scientific | Thermo Fisher Scientific K.K. (Japanese subsidiary) |
| HiScribe T7 / GMP-grade IVT reagents | New England Biolabs | Not yet confirmed |
| GMP-grade IVT enzymes and nucleotides | Merck | Merck Ltd., Japan (Japanese subsidiary, Life Science) |
| T7 RNA Polymerase / RQ1 RNase-Free DNase | Promega | Not yet confirmed |
| GMP mRNA raw materials and enzymes | Aldevron | Not yet confirmed |
| Enzymes and nucleotide raw materials for IVT | Roche CustomBiotech | Not yet confirmed |
“Where to buy in Japan” shows only sales relationships we have confirmed on the company’s or the distributor’s own website. “Not yet confirmed” means we have not checked yet, not that the product is unavailable in Japan. Product names link to the maker’s own page.