Orthogonal tRNA aaRS
15 listings from 12 suppliers · 1 Japanese maker
Japanese name: 直交tRNA／aaRS（アンバーサプレッサー系）
Orthogonal tRNA/aaRS pairs are engineered aminoacyl-tRNA synthetases and suppressor tRNAs that reassign the amber codon so a non-natural amino acid can be incorporated at a chosen site. This genetic code expansion system underlies precise protein modification. The main choices are which host the pair fits, such as E. coli or mammalian cells, and which ncAA it incorporates. This category covers expression plasmids, engineered hosts, cell-free systems and amino acid substrates.
| Product | Maker | Where to buy in Japan |
|---|---|---|
| Genetic Code Expansion plasmid collection | Addgene | Not yet confirmed |
| pEVOL_PylRS(AF)-tRNA (#223511) | Addgene | Not yet confirmed |
| Mm-PylRS-AF/Pyl-tRNACUA (#122650) | Addgene | Not yet confirmed |
| pMega-MaPylRS (#200225) | Addgene | Not yet confirmed |
| Mm-PylRS-AF-Pyl-tRNACUA vector | Novoprolabs | Not yet confirmed |
| Product | Maker | Where to buy in Japan |
|---|---|---|
| RFzero (RF-1-deficient engineered E. coli strain series) | RIKENJP maker | From the maker |
| XpressCF+ (cell-free synthesis system with orthogonal aaRS) | Sutro Biopharma | Not yet confirmed |
| Product | Maker | Where to buy in Japan |
|---|---|---|
| Click Amino Acid TCO*A (trans-Cyclooct-2-en-L-Lysine, SC-8008) | SiChem | Not yet confirmed |
| 4-Azido-L-phenylalanine (AzF, CLK-AA001) | Jena Bioscience | Not yet confirmed |
| 4-Azido-L-phenylalanine (BCAA-001-100) | baseclick | Not yet confirmed |
| H-L-Tyr(Propargyl)-OH (alkyne tyrosine) | Iris Biotech | Not yet confirmed |
| trans-Cyclooctene-L-Lysine TCO*A | Sirius Fine Chemicals | Not yet confirmed |
| 4-Azido-L-phenylalanine (909564) | Merck | Merck Ltd., Japan (Japanese subsidiary, Life Science) |
| trans-Cyclooct-2-en-L-Lysine (CAS 1801936-26-4) | BOC Sciences | Not yet confirmed |
| N-TCO-L-lysine | MedChemExpress | Not yet confirmed |
“Where to buy in Japan” shows only sales relationships we have confirmed on the company’s or the distributor’s own website. “Not yet confirmed” means we have not checked yet, not that the product is unavailable in Japan. Product names link to the maker’s own page.