Disulfide reduction alkylation reagents
18 listings from 8 suppliers · 2 Japanese makers
Japanese name: 還元剤・アルキル化剤（DTT／TCEP／IAA・分析グレード）
Reducing agents (DTT, TCEP) break disulfide bonds, and alkylating agents such as iodoacetamide cap the freed thiols. These analytical-grade reagents prepare antibody samples for CE-SDS and LC-MS. Buyers pick the reducing agent first: TCEP, easier to handle for odor and stability, or DTT, the standard and cheaper choice. They then match an alkylating agent or pretreatment kit to the method. For trace analysis, high purity and single-use portions help reproducibility. Each product below is shown with its maker and the company that handles it in Japan.
| Product | Maker | Where to buy in Japan |
|---|---|---|
| Bond-Breaker TCEP Solution, Neutral pH (0.5M) | Thermo Fisher Scientific | Thermo Fisher Scientific K.K. (Japanese subsidiary) |
| TCEP hydrochloride (C4706, ≥98%) | Sigma-Aldrich | Not yet confirmed |
| Tris(2-carboxyethyl)phosphine Hydrochloride (T1656, >98.0%) | TCIJP maker | From the maker |
| TCEP-HCl (CAS 51805-45-9, ≥98%) | Gold Biotechnology | Not yet confirmed |
| TCEP hydrochloride | Hampton Research | Not yet confirmed |
| Product | Maker | Where to buy in Japan |
|---|---|---|
| DL-Dithiothreitol, for molecular biology (D9779) | Sigma-Aldrich | Not yet confirmed |
| DL-Dithiothreitol BioUltra (43815, ≥99.5%) | Sigma-Aldrich | Not yet confirmed |
| 1mol/L (±)-Dithiothreitol (DTT) solution | FUJIFILM WakoJP maker | From the maker |
| (±)-Dithiothreitol (for molecular biology) | FUJIFILM WakoJP maker | From the maker |
| DL-Dithiothreitol (D1071) | TCIJP maker | From the maker |
| Product | Maker | Where to buy in Japan |
|---|---|---|
| Iodoacetamide BioUltra (I1149, ≥99% NMR) | Sigma-Aldrich | Not yet confirmed |
| Iodoacetamide, Single-use vial (A3221) | Sigma-Aldrich | Not yet confirmed |
| Pierce Iodoacetamide, Single-Use / No-Weigh (A39271) | Thermo Fisher Scientific | Thermo Fisher Scientific K.K. (Japanese subsidiary) |
| N-Ethylmaleimide (NEM, 04260, ≥99% HPLC) | Sigma-Aldrich | Not yet confirmed |
| Product | Maker | Where to buy in Japan |
|---|---|---|
| CE-SDS Biologics Purity Analysis Kit (C30085 and others) | SCIEX | Not yet confirmed |
| SDS-MW Analysis Kit (for PA 800 plus) | SCIEX | Not yet confirmed |
| FOCUS Protein Reduction-Alkylation Kit (786-231) | G-Biosciences | Not yet confirmed |
| FOCUS Protein Reductant (TCEP, 786-230) | G-Biosciences | Not yet confirmed |
“Where to buy in Japan” shows only sales relationships we have confirmed on the company’s or the distributor’s own website. “Not yet confirmed” means we have not checked yet, not that the product is unavailable in Japan. Product names link to the maker’s own page.